When Barry Huffman (the man who plays Duffman) undergoes hip replacement surgery following an injury during a parade and retires, Duff Beer's owner Howard K. Duff VII sets up a reality show called "So You Think You Can Duff" presented by Cat Deeley in order to find his replacement. The judges for this competition are Der Zip Zorp (a best-selling Electronica artist that wears a computer monitor-shaped helmet), Missy LeBeau (a former Duff Girl and current senator from Oklahoma), and Rajneesh Superstar (a billionaire Mumbai entrepreneur). The competition is fierce until only Homer Simpson and one other competitor remained. Homer wins the competition after the other contestant was disqualified upon Der Zip Zorp detecting a tattoo of Duff Beer's competitor Olde Ogdenville Ale on his back. Howard K. Duff VII tells him that he has inserted him with a chip that will reveal if he drinks, because he must stay sober on the job.
While sober, Homer sees the misery that Duff is causing to the people and environment of Springfield. At a motor racing event, he gives out alcohol-free beer as a placebo in an attempt to convince the audience that alcohol is not essential for a good time. This angers them, and they form an angry mob. Howard K. Duff fires Homer and tells him that there was no chip, so Homer returns to heavy drinking.
Following the incident, Howard K. Duff tracks down Barry Huffman (who is now working at a coffee shop) and convinces him to take his old job back.