While Homer, Bart and Lisa are watching television, Marge announces that she is going to audition for a local musical production of A Streetcar Named Desire, and she wants to meet new people because she usually spends all day caring for Maggie. The rest of the family pay no attention and continue to watch television.
The musical is called "Oh, Streetcar!", which is directed by Llewellyn Sinclair. After Ned Flanders is cast as Stanley Kowalski, Marge auditions for Blanche DuBois. Llewellyn immediately rejects Marge, explaining that Blanche is supposed to be a "delicate flower being trampled by an uncouth lout". However, as a dejected Marge calls home and takes Homer's dinner order, Llewellyn realizes that she is perfect for the role.
The next day, Maggie causes distractions when Marge brings her to rehearsal, so Llewellyn tells Marge to enroll the baby at the daycare center called Ayn Rand School for Tots which is run by his sister Ms. Sinclair, who immediately confiscates Maggie's pacifier. Maggie and the other babies later engage in an attempt to retrieve their pacifiers, but Ms. Sinclair thwarts their efforts and sends Maggie to a playpen.
During rehearsal, Marge struggles with a scene in which Blanche is supposed to break a glass bottle and attack Stanley, but she cannot muster enough anger towards the Stanley character to break the bottle. After coming home, Marge asks Homer to help her learn her lines, but Homer is disinterested. The day before the performance, Marge and Ned are again practising the bottle scene as Homer arrives to drive Marge home. Homer repeatedly interrupts the rehearsal. Imagining that Stanley is Homer, Marge finally smashes the bottle and lunges at Ned.
The next day at the Ayn Rand School for Tots, Maggie again attempts to regain the pacifiers and this time succeeds. Homer arrives to pick her up and he and his children go to watch the musical. Homer immediately falls into boredom, but he perks up when Marge appears on stage and becomes saddened over the way Stanley treats Blanche. All the while Homer slowly picks up the plot and Marge's feelings along with it. At the end of the musical, Marge receives a warm reaction from the crowd, but she misinterprets Homer's sadness for boredom. Afterwards, she confronts him with hostility, but Homer is able to explain that he was genuinely moved by Blanche's situation. Thus, he reacted with sadness because he wanted to be the husband that she deserves to have in her life who loved her, not like Stanley who neglects and mistreats her. Marge realizes that Homer really did watch the musical, and the two happily leave the theater.