Many of Springfield's residents purchase "Juice Looseners" through the mail, which are inefficient and loud juicers built in Japan and shipped from there. One of the assembly line workers has the flu and coughs into the box destined for Homer, filling it with airborne germs. When the Juice Looseners arrive in Springfield, the dreaded Osaka Flu hits the town and many of the townspeople are affected by the illness. Due to exhaustion from having to look after the rest of her ill family, Marge accidentally forgets to pay for Grampa's bottle of bourbon when shopping at the Kwik-E-Mart. She is then arrested for shoplifting. Chief Wiggum tells Mayor Quimby about the arrest in confidence, and Quimby later reveals this fact to everyone in town during a public address. Marge's reputation is lowered dramatically among the townspeople, who now distrust her around their possessions. The family hires Lionel Hutz to defend Marge at her trial, but Hutz loses the case and the jury finds Marge guilty. She is sentenced to 30 days imprisonment at Springfield Women's Prison.
Marge's absence is felt at home as Homer and the rest of the family struggles to cope without her. Without Marge, the house shortly becomes a complete wreck. The annual bake sale also suffers – without Marge's marshmallow squares, the Springfield Park Commission fails to raise enough money to pay for a statue of Abraham Lincoln. Instead they purchase one of Jimmy Carter. The townspeople are enraged by this, and riot. When Marge is released from jail, the townspeople welcome her back and apologize for suspecting her. They even unveil a statue for Marge, though it is just the Carter statue with Marge's hair added to it. The last scene shows Bart and Lisa playing on the statue, which has been converted into a tether ball post.